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The perricone weight-loss diet: a simple 3-part program to lose the fat, the wrinkles, and the years [nicholas perricone] on amazon.com. *free* shipping on qualifying offers. from #1 new york times bestselling author nicholas perricone– respected physician, award-winning research scientist. Weight loss, in the context of medicine, health, or physical fitness, refers to a reduction of the total body mass, due to a mean loss of fluid, body fat or adipose tissue or lean mass, namely bone mineral deposits, muscle, tendon, and other connective tissue.. In a six-month clinical trial, participants who followed ww freestyle saw great weight loss and impressive changes on and off the scale..